Results
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| Property | Organism | Value | Units | ID | Details |
|---|---|---|---|---|---|
| Concentration of EGF in blood serum | Human Homo sapiens | 62.5 | pM | 104827 | Brzezinski J, Lewinski... |
| Ligand [murine EGF, Epidermal Growth Factor] clearance when saturating concentrations of EGF were perfused through a liver at 35˚C in hepatocyte | Rat Rattus norvegicus | in rapid primary phase 20,000: in slower secondary phase 2,500 | molecules/min/cell | 112726 | Dunn WA, Hubbard AL.... |
| Concentration of EGF in PC12 cells | Rat Rattus norvegicus | 0.1 (Table - link) | µM | 100897 | Brightman FA and Fell DA... |
| Number of EGF receptors per fetal lung cell | Rat Rattus norvegicus | 25500 | unitless | 101360 | Waters CM, Oberg KC,... |
| Quantitative mapping of EGF (Epidermal growth factor)-triggered subcellular translocation events in HeLa cell | Human Homo sapiens | Figure - link | protein copies | 112705 | Itzhak DN, Tyanova S... |
| EGF [Epidermal Growth Factor] internalization and transit the early endosome in HMEC [Human Mammary Epithelial Cells] | Human Homo sapiens | t1/2 of EGF internalization ~5: transit the early endosome ≥20 | min | 112722 | Burke P, Schooler K,... |
| Number of EGFR [Epidermal Growth Factor Receptor] in hepatocyte | Rat Rattus norvegicus | in perfused liver 150,000: in vitro ~300,000 | molecules/cell | 112725 | Dunn WA, Hubbard AL.... |
| Total number of EGFR (surface and intracellular) in PC12 cells | Rat Rattus norvegicus | 15000 (Table - link) | molecules/cell | 100899 | Brightman FA and Fell DA... |
| Rate of receptor internalization in PC12 cells | Rat Rattus norvegicus | 0.7 (Table - link) | min^-1 | 100896 | Brightman FA and Fell DA... |
| EGFR (epidermal growth factor receptor) levels (see comments section for normal cell types) | Mammals | normal cells 5,000 to 200,000: cancer cells ≤2––3×10^6 | EGFR/cell | 112720 | Sorkin A, Duex JE. Q... |
| Turnover rate of GAP (Ras GTPase activating protein) in PC12 cells | Rat Rattus norvegicus | 720 (Table - link) | min^-1 | 105647 | Brightman FA and Fell DA... |
| kcat of p38α (MAPK14) protein kinase with EGFR as substrate | Bacteria Escherichia coli | 31.6 (±1.1) | sec^-1 | 110568 | Zhang YY, Mei ZQ, Wu JW... |
| Concentration of Raf in HeLa cells | Mammalian tissue culture cell | 0.0057 (Table - link) | µM | 100890 | Dynamics of the Ras/ERK... |
| Number of copies of the MAP Kinase cascade proteins in a cell | Human Homo sapiens | Table - link | N/A | 104828 | Schoeberl B, Eichler-Jonsson... |
| Number of all plasma membrane transporters & other integral membrane proteins in HeLa cell | Human Homo sapiens | all plasma membrane transporters 4×10^7copies: other integral membrane proteins ~3×10^7copies | protein copies | 112706 | Itzhak DN, Tyanova S... |
| Top 20 most abundant proteins in each of mitochondrion, plasma membrane & endoplasmic reticulum of HeLa cell | Human Homo sapiens | Figure - link | % of protein organelle mass | 112704 | Itzhak DN, Tyanova S... |
| HER2 concentration (for cell types see comments section) | Human Homo sapiens | in mammary epithelial cells <10,000: in HB2 cells ~60,000 | molecules/cell | 112721 | Burke P, Schooler K,... |
| concentration of Ras in HeLa cells | Human Homo sapiens | 1.6 | µM | 100889 | Schoeberl B, Eichler-Jonsson... |
| concentration of Raf in HeLa cells | Mammalian tissue culture cell | 2.1 | µM | 100891 | Schoeberl B, Eichler-Jonsson... |
| concentration of MEK in HeLa cells | Mammalian tissue culture cell | 3.1 | µM | 100884 | Schoeberl B, Eichler-Jonsson... |