Results
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| Property | Organism | Value | Units | ID | Details |
|---|---|---|---|---|---|
| Fraction of misfolded proteome degraded by Lon ATP-dependent AAA+ protease | Bacteria Escherichia coli | ~50 | % | 111875 | Gur E, Sauer RT. Degrons... |
| Number of ATPs consumed by one Hsp70 to effectively unfold a single misfolded protein into an intermediate in vitro | Bacteria Escherichia coli | 5 | ATP | 113282 | Sharma SK, De los Rios P... |
| Fraction of newly synthesized proteins that are rapidly degraded | Unspecified | ~30 | % | 113409 | Glembotski CC. Endoplasmic... |
| Percentage of 'long lived' proteins that are degraded per hour | Mammals | 1 to 2 | %/hour | 108153 | Goldberg AL. Protein... |
| Percentage of newly synthesized proteins that are degraded by proteasome within minutes of synthesis | Eukaryotes | ≤30 | % | 108154 | Goldberg AL. Protein... |
| Fraction of proteome that is secreted and membrane proteins | Eukaryotes | ~30 | % | 113358 | Wang F, Durfee LA, Huibregtse... |
| Number of proteins that are part of the proteostasis network (PN) (total of ~1,300 different proteins) | Mammals | proteins involved in: protein biogenesis ~400: conformational maintenance ~300: degradation ~700 | different proteins | 113352 | Kim YE, Hipp MS, Bracher A... |
| Size of aggregosome | Generic | 2-10 Table - link | µm | 104581 | Spector DL. SnapShot:... |
| Fraction of newly synthesized proteins that are very rapidly degraded by the ubiquitin-proteasome system (UPS) | Eukaryotes | 6 - 30 | % | 113356 | Wang F, Durfee LA, Huibregtse... |
| Percent of proteins that are rapidly degraded (with half life of ~1 hour) | Bacteria Escherichia coli | 2 to 7 | % | 108404 | Nath K, Koch AL. Protein... |
| Number of cytosolic proteins | Bacteria Escherichia coli | 2,400 | proteins | 110575 | Kerner MJ, Naylor DJ... |
| Apparent Vmax, Number of refolded luciferase molecules per DnaK molecule | Bacteria Escherichia coli | ~5.4 | refolded luciferase/DnaK | 113281 | Sharma SK, De los Rios P... |
| Summary of in vitro chaperone reactions with attempts to correlate folding with ATP-costs | Bacteria Escherichia coli | Table - link | N/A | 113283 | Sharma SK, De los Rios P... |
| Number of proteins/mRNA | Budding yeast Saccharomyces cerevisiae | 5600 (4,000 to 7,000) | proteins/mRNA | 104185 | Lu P, Vogel C, Wang R... |
| Number of proteins/mRNA | Bacteria Escherichia coli | 540 (300 to 600) | proteins/mRNA | 104186 | Lu P, Vogel C, Wang R... |
| Number of proteins in chloroplast | Chloroplast | ~3,000 | proteins | 113133 | Andreas Bracher, Spencer... |
| Estimated translation rate | Fungus Mucor racemosus | 5 - 9 | aa/sec | 113359 | Wang F, Durfee LA, Huibregtse... |
| Fraction of ribosomes that are in CTUs (cotranslational ubiquitination stalled complexes) | Eukaryotes | ~22 - 27 | % | 113360 | Wang F, Durfee LA, Huibregtse... |
| Fraction of nascent polypeptides associated with Hsp70 SSB | Budding yeast Saccharomyces cerevisiae | ~45 | % | 113361 | Wang F, Durfee LA, Huibregtse... |
| Quantified proteins | Bacteria Mycoplasma pneumoniae | Table - link | copies/cell | 108356 | Maier T, Schmidt A, Güell M... |