Diffusion controlled limit of enzymatic reaction rate
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| Range | 1e-8-1e-9 1/(sec*Molar) |
|---|---|
| Organism | constants |
| Reference | Nelson & Cox, Lehninger's Principles of Biochemistry 4th Edition, 2004, WH Freeman & Co, Table 6-4 pp.207 |
| Comments | There is an upper limit to Kcat/Km, imposed by the rate at which E and S can diffuse together in an aqueous solution. This diffusion controlled limit is 10^8 to 10^9 M^-1*s^-1, and many enzymes have a kcat/Km near this range |
| Entered by | Uri M |
| ID | 103916 |