Mean dwell time of transcripts at transcription site during G1

Range 770±260 PP7- MDN1 transncript: 140±30 MDN1-PP7 transcript Sec
Organism Budding yeast Saccharomyces cerevisiae
Reference Larson DR, Zenklusen D, Wu B, Chao JA, Singer RH. Real-time observation of transcription initiation and elongation on an endogenous yeast gene. Science. 2011 Apr 22 332(6028):475-8. p.477 right column 2nd paragraphPubMed ID21512033
Method An idealized fluorescence time trace for transcription of a single pre-mRNA can be described by an autocorrelation function G(t), which is a discrete autocorrelation over all the transition probabilities for RNAPII
Comments The total dwell time of a transcript (T), includes elongation and termination, and the transcript initiation rate (c).
Entered by Uri M
ID 106353