| Range |
6 - 7 molecules/ribosome
|
| Organism |
Bacteria Escherichia coli |
| Reference |
Klumpp S, Scott M, Pedersen S, Hwa T. Molecular crowding limits translation and cell growth. Proc Natl Acad Sci U S A. 2013 Oct 15 110(42):16754-9. doi: 10.1073/pnas.1310377110. p.16754 left column bottom paragraphPubMed ID24082144
|
| Primary Source |
Neidhardt FC, Bloch PL, Pedersen S, Reeh S (1977) Chemical measurement of steadystate levels of ten aminoacyl-transfer ribonucleic acid synthetases in Escherichia coli. J Bacteriol 129: 378–387.PubMed ID318645
|
| Comments |
"In addition to their high ribosome content, rapidly growing
bacteria also contain large amounts of other proteins associated
with translation. In particular, the most abundant protein in fastgrowing
E. coli is elongation factor Tu (EF-Tu), with about six to
seven molecules per ribosome (primary source), and accounting for up to
10% of the total protein mass under conditions of rapid growth
(refs 2, 16 BNID 106415)." |
| Entered by |
Uri M |
| ID |
110048 |