Number of barbed ends supporting actin assembly per µm of margin

Value 241 1/µm Range: ±100 Table - link 1/µm
Organism Mammalian tissue culture cell
Reference Abraham VC, Krishnamurthi V, Taylor DL, Lanni F. The actin-based nanomachine at the leading edge of migrating cells. Biophys J. 1999 Sep77(3):1721-32 abstract, p.1728 table 2 & left column bottom paragraphPubMed ID10465781
Primary Source See pointers to refs and refs beneath table
Comments "[Researchers] are able to estimate the number of free filament ends, 241±100/µm of lamellipodial margin, a parameter that is only dependent on dL/dS and the angle subtended by individual filaments and the margin (Table 2). [Their] result is similar to an estimate of 110–130 filament ends/µm obtained via analysis of high-resolution electron micrographs of fibroblast lamellipodia (see Materials and Methods)."
Entered by Uri M
ID 111061