Mean sizes of peptides generated by α3∆N and wild type core particle of proteasome

Range Table - link residues (amino acids)
Organism Budding yeast Saccharomyces cerevisiae
Reference Köhler A, Cascio P, Leggett DS, Woo KM, Goldberg AL, Finley D. The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release. Mol Cell. 2001 Jun7(6):1143-52. p.1149 table 1PubMed ID11430818
Method "Mean sizes were calculated from the distributions of products obtained by size exclusion chromatography, assuming an average molecular weight of 110 Da for each residue."
Comments "By combining the data for casein and ovalbumin, a mean length of 7.6 residues was obtained for products of wild-type CP, and for openchannel particles, 9.6. These differences were shown to be highly significant by the Mann-Whitney U test (for casein p0.01, for ovalbumin p0.001). An even larger relative difference was seen in the median peptide size (Table 1)."
Entered by Uri M
ID 109958