Average copy number of pUC plasmid

Range ~55 Copies/cell
Organism Bacteria Escherichia coli
Reference Megerle JA, Fritz G, Gerland U, Jung K, Rädler JO. Timing and dynamics of single cell gene expression in the arabinose utilization system. Biophys J. 2008 Aug95(4):2103-15. p.2107 left column 2nd paragraphPubMed ID18469087
Primary Source Lin-Chao S, Chen WT, Wong TT. High copy number of the pUC plasmid results from a Rom/Rop-suppressible point mutation in RNA II. Mol Microbiol. 1992 Nov6(22):3385-93.PubMed ID1283002
Comments The plasmid pBAD24 has an average copy number comparable to pUC (29), which is present in ~55 copies per cell (primary source).
Entered by Uri M
ID 108259