Euchromatic genome Size

Value 2.5e+9 Base pairs
Organism Mouse Mus musculus
Reference Mouse Genome Sequencing Consortium (MGSC), Initial sequencing and comparative analysis of the mouse genome, Nature. 2002 Dec 5 420(6915):520-62. p.524 right column top sentence & p.525 table 3PubMed ID12466850
Method P.522 right column 3rd paragraph: "...[investigators] adopted a hybrid strategy for sequencing the mouse genome. The strategy has four components: (1) production of a BAC-based physical map of the mouse genome by fingerprinting and sequencing the ends of clones of a Bacterial Artificial Chromosome (BAC) library (ref 44) (2) WGS [Whole genome] sequencing to approximately sevenfold coverage and assembly to generate an initial draft genome sequence (3) hierarchical shotgun sequencing of BAC clones covering the mouse genome combined with the WGS data to create a hybrid WGS-BAC assembly and (4) production of a finished sequence by using the BAC clones as a template for directed finishing."
Comments P.524 left column bottom paragraph: "On the basis of the estimated sizes of the ultracontigs and gaps between them, the total length of the euchromatic mouse genome was estimated to be about 2.5Gb (see Supplementary Information), or about 14% smaller than that of the euchromatic human genome (about 2.9Gb [see BNID 100 396])(table 3)." For size of 2,493Mb see table 3. For total genome size of 2.6Gbp see BNID 100308
Entered by Ron Milo - Admin
ID 100305