Fraction of cell dry mass that is ribosomes during exponential phase

Value 30 % of cell dry weight
Organism Bacteria Escherichia coli
Reference Soler-Bistué A et al., Genomic location of the major ribosomal protein gene locus determines Vibrio cholerae global growth and infectivity. PLoS Genet. 2015 Apr 13 11(4):e1005156. doi: 10.1371/journal.pgen.1005156. p.2/21 bottom paragraphPubMed ID25875621
Primary Source [18] Kaczanowska M, Ryden-Aulin M. Ribosome biogenesis and the translation process in Escherichia coli. Microbiology and molecular biology reviews: MMBR. 2007 71(3):477–94. doi: 10.1128/MMBR.00013- 07 PubMed Central PMCID: PMC2168646.PubMed ID17804668
Comments P.2/21 bottom paragraph:"Comparative genomic studies revealed that in fast-growing bacteria, essential genes involved in the expression of genetic information such as RNA polymerase (RNAP), ribosomal genes and specific tRNAs are found near oriC [ref 16]. In parallel, it has been observed that both ribosome and RNA polymerase molecule counts can vary by one order of magnitude according to the cell physiological state, reaching its peak at the exponential phase. This is when the growth rate is maximal and bacteria need the highest synthesis capacity [ref 17]. In these circumstances, ribosomes account for 30% of the cell’s dry mass [primary source 18]." See BNID 109048
Entered by Uri M
ID 112365