Diffusion coefficient of cGMP in the disc stacks of ROS (Rod Outer Segment)

Value 170 μm^2/sec
Organism Unspecified
Reference Dumke CL, Arshavsky VY, Calvert PD, Bownds MD, Pugh EN Jr. Rod outer segment structure influences the apparent kinetic parameters of cyclic GMP phosphodiesterase. J Gen Physiol. 1994 Jun103(6):1071-98. p.1091 top paragraph and p.1086 3rd paragraphPubMed ID7931138
Comments "For the fully open disc stack model to account for the approximate fourfold Km shift of the small fragment preparation, it was necessary to assume that Dr, the radial diffusion coefficient of cGMP in the disc stacks, is 170µm^2/sec."
Entered by Uri M
ID 109738