Compaction of nucleoid

Range ~1.5 mm DNA contour length within a 3µm long X 1µm diameter cell
Organism Bacteria Escherichia coli
Reference Bakshi S1, Siryaporn A, Goulian M, Weisshaar JC. Superresolution imaging of ribosomes and RNA polymerase in live Escherichia coli cells. Mol Microbiol. 2012 Jul85(1):21-38. doi: 10.1111/j.1365-2958.2012.08081.x. p.21 right column top paragraphPubMed ID22624875
Method Superresolution fluorescence microscopy
Comments "In Escherichia coli, the chromosomal DNA is ‘condensed’ into an irregularly shaped, central region called the nucleoid (Robinow and Kellenberger, 1994). The nucleoid does not fill the entire cytoplasmic volume, in spite of severe compaction of ~1.5 mm of DNA contour length within a 3µm long X 1µm diameter cell."
Entered by Uri M
ID 110184