Biomechanical parameter changes in Opg-/- mice upon raloxifene treatment

Range Table - link
Organism Mouse Mus musculus
Reference Yan MZ et al., Raloxifene inhibits bone loss and improves bone strength through an Opg-independent mechanism. Endocrine. 2010 Feb37(1):55-61 p.58 table 1PubMed ID20963556
Comments As shown in Table 1, ultimate load, ultimate stress, and Young’s modulus of Opg-/- mice were significantly decreased as compared with those of wild-type mice. After treatment with raloxifene, the values of these indexes were significantly increased for both lumbar vertebrae and femur bones.
Entered by Uri M
ID 106645