Volume of MCF-7 (breast cancer) cell

Value 1760 µm^3
Organism Human Homo sapiens
Reference Wagner BA, Venkataraman S, Buettner GR. The rate of oxygen utilization by cells. Free Radic Biol Med. 2011 Aug 1 51(3):700-12. doi: 10.1016/j.freeradbiomed.2011.05.024 p.707 right column bottom paragraphPubMed ID21664270
Primary Source [60] Gamcsik MP, Millis KK, Colvin OM. Noninvasive detection of elevated glutathione levels in MCF-7 cells resistant to 4-hydroperoxycyclophosphamide. Cancer Res. 1995 May 15 55(10):2012-6.PubMed ID7743493
Method Primary source abstract: "Native human mammary MCF-7 adenocarcinoma cells and a subline displaying resistance to 4-hydroperoxycyclophosphamide, the chemically activated form of cyclophosphamide, were grown as multicellular spheroids or on a collagen sponge matrix and perfused for study by 31P and 13C nuclear magnetic resonance spectroscopy."
Comments P.707 right column bottom paragraph: "The volume of cells varies considerably, from ≈ 0.5 fl (5×10^−4 pl) for a bacterial cell [refs 55, 56] to ≈ 40 fl (4×10^−2 pl) for yeast [ref 57], ≈ 90 fl (9×10^−2 pl) for human erythrocytes [ref 58 BNID 115152], 0.30 pl for human neutrophils [BNID 115153 ref 59], 1.76 pl for MCF-7 cells [primary source], and 6.2 pl for rat hepatocytes [ref 53 BNID 115150]."
Entered by Uri M
ID 115154