Composition of myelin

Range lipids 70 - 80: protein 20 - 30 %
Organism Metazoa animals
Reference Hildebrand C, Remahl S, Persson H, Bjartmar C. Myelinated nerve fibres in the CNS. Prog Neurobiol. 1993 Mar40(3):319-84 p.337 right column bottom paragraph & p.338 left column 2nd paragraphPubMed ID8441812
Comments P.337 right column bottom paragraph: "Lipids constitute 70-80% of the myelin material, but there is no known myelin-specific lipid. A distinguishing feature of myelin is a high content of galactolipids (cerebroside and sulphatide), cholesterol and the plasmalogen form of ethanolamine phosphoglyceride. Together these three lipids comprise about 65% of the total lipids (Norton and Cammer, 1984)." P.338 left column 2nd paragraph: "Since the proteins, which constitute some 20-30% of the myelin material, account for the encephalitogenic properties of myelin, they have attracted much interest."
Entered by Uri M
ID 114494