Affinity of tetR for anhydrotetracycline-Mg+
| Value | 98 picomolar |
|---|---|
| Organism | Unspecified |
| Reference | Scholz, O., Schubert, P., Kintrup, M., and Hillen, W. (2000). Tet repressor induction without Mg2+. Biochemistry 39, 10914–10920.PubMed ID10978179 |
| Method | Fitting of anhydrotetracycline fluorescence as a function of anhydrotetracycline and tetR concentrations. |
| Comments | Abstract: "Of all tc compounds tested so far, atc has the highest affinity for TetR, with a K(A) of 9.8×10^11 M^(-1) in the presence of Mg(2+) and 6.5×10^(7)×M^(-1) without Mg(2+)." |
| Entered by | Avi Flamholz |
| ID | 113019 |