Comments |
P.628 2nd paragraph:"It is possible that species differences within the mammalian or differences between various types of nerves could account for some of these divergent rate determinations. To assess such factors a more direct method of analysing the rate within the nerve fibres is required, one which has been used in this laboratory for the last several years. An amino acid precursor ([3H]leucine) is injected either into the cat lumbar seventh (L7) dorsal root ganglion or into the ventral horn of the L7 segment of the spinal cord, and after a period of downflow a crest of labelled activity in the sciatic nerve shows the presence of fast axoplasmic transport (Ochs, Sabri & Johnson, 1969 Ochs & Ranish, 1969). This crest contains protein incorporated materials which move down the nerve in a linear and regular fashion at a rate of about 400-410 mm/day." |