Range |
50.7% pyruvate: 6.5% cell biomass: 36.3% glycine synthesis: remainder for other metabolites % of serine
|
Organism |
Bacteria Escherichia coli |
Reference |
Selvarasu S. et al., Characterizing Escherichia coli DH5alpha growth and metabolism in a complex medium using genome-scale flux analysis. Biotechnol Bioeng. 2009 Feb 15 102(3):923-34. doi: 10.1002/bit.22119. p.926 right column bottom paragraphPubMed ID18853410
|
Comments |
"While 50.7% of serine flux
was directed towards pyruvate, 6.5% was used for cell
biomass, 36.3% for glycine synthesis (1.22 mmol/gDCW/h) and the remaining for other metabolites (O-acetyl-L-serine
and phosphatidylserine). The resulting flux distribution
suggested that the majority of serine was assimilated for
pyruvate production leading to acetate secretion." |
Entered by |
Uri M |
ID |
111287 |