Characteristic range for transition errors

Range (0.6-3)x10^-4 substitution/bp
Organism Bacteria Escherichia coli
Reference Imashimizu M, Oshima T, Lubkowska L, Kashlev M. Direct assessment of transcription fidelity by high-resolution RNA sequencing. Nucleic Acids Res. 2013 Oct41(19):9090-104. doi: 10.1093/nar/gkt698. p.9095 left columnPubMed ID23925128
Method Based on high coverage sequencing.
Comments "[Investigators] observed an up to 2-fold Mn2+-dependent increase in errors for G?A and T(U)?C transitions in a majority of cDNA positions in the error range from 3×10^-4 to 6×10^-5 b^-1." The value stated is just the charactaristic range over which transcription errors are observed for different locations
Entered by Ron Milo - Admin
ID 111146