Fraction by which biological membranes elastically expand before rupture

Range <3 %
Organism Generic
Reference Dai J, Sheetz MP, Wan X, Morris CE (1998) Membrane tension in swelling and shrinking molluscan neurons. J Neurosci 18: 6681–6692 p.6681 left column top paragraphPubMed ID9712640
Primary Source Nichol JA, Hutter OF (1996) Tensile strength and dilatational elasticity of giant sarcolemmal vesicles shed from rabbit muscle. J Physiol (Lond) 493: 187–198.PubMed ID8735704
Comments "Biological membranes expand elastically by <3% before rupture (primary source). Beyond this limit, membrane area must be augmented to avoid lysis. Membrane capacitance changes suggest that during swelling, membrane is added from internal stores and that on shrinking, excess membrane is reinternalized (Sukhorukov et al., 1993 Wan et al., 1995). In neurons and muscle cells (Krolenko et al., 1995 Reuzeau et al., 1995), membrane invaginates as vacuole-like dilations (VLDs) during the shrinking phase of swell–shrink cycles, effects that are mechanically mediated."
Entered by Uri M
ID 110847