Urea permeability of red cells from different donors

Range Table - link
Organism Human Homo sapiens
Reference Brahm J. Urea permeability of human red cells. J Gen Physiol. 1983 Jul82(1):1-23. p.5 table IPubMed ID6411854
Method "The rate of unidirectional [14C]urea efflux from human red cells was determined in the self-exchange and net efflux modes with the continuous flow tube method...The experiments were performed at 25°C, pH 7.2, and 1 mM urea. The permeability coefficients in the table are average values of two to four self-exchange experiments carried out with the continuous flow tube technique. Standard deviations of the rate coefficients are in parentheses."
Comments "Table I shows the results of determinations of urea permeability of different donors. The experiments were performed with a urea concentration of 1 mM at 25°C and pH 7.2. The permeability coefficients varied by a factor of >2. The difference was a constant finding, because no day-to-day variation could be detected. Care was therefore taken to ensure that each series of experiments was performed with blood from the same donor."
Entered by Uri M
ID 110728