| Value |
7.57
unitless
Range: ±0.22 Table - link unitless
|
| Organism |
Rat Rattus norvegicus |
| Reference |
Crespo-Armas A, Mowbray J. The rapid alteration by tri-iodo-L-thyronine in vivo of both the ADP/O ratio and the apparent H+/O ratio in hypothyroid-rat liver mitochondria. Biochem J. 1987 Feb 1 241(3):657-61. p.660 table 2 top row, right-most column & table 1 top row, column left of right-most columnPubMed ID3036069
|
| Method |
"...studies on the decreased phosphorylating ability
of hypothyroid-rat mitochondria are complemented by 31P n.m.r. measurements by the saturation transfer
method of ATP synthetase compared with 02 uptake in perfused hearts from hypothyroid rats [14], and by measurements of the effects of T3 on adenine nucleotide concentrations in freeze-clamped [3] and perfused [15,16]
hypothyroid-rat livers." |
| Comments |
"Table 2 presents the results of
experiments aimed at measuring ?p in State 3 in liver mitochondria from normal, thyroidectomized and thyroidectomized/hormone-treated animals...Comparing the ADP/O and H+/O ratios measured on
the same preparations of mitochondria shows that the
former is decreased to 61 % and the latter to 58% of
normal by thyroidectomy. At 15 min after intravenous
hormone injection, the mitochondria show ADP/O and
H+/O ratios of 93% and 91% of the euthyroid value." |
| Entered by |
Uri M |
| ID |
110654 |