Number of proteins synthesized per generation for three different growth conditions

Range Excel Table - link protein molecules/generation
Organism Bacteria Escherichia coli
Reference Li GW, Burkhardt D, Gross C, Weissman JS. Quantifying absolute protein synthesis rates reveals principles underlying allocation of cellular resources. Cell. 2014 Apr 24 157(3):624-35. doi: 10.1016/j.cell.2014.02.033. Supplemental table S1PubMed ID24766808
Method "To broadly evaluate the rates of protein synthesis, [researchers] performed ribosome profiling in E. coli grown in different growth conditions with high sequencing depth (90 million fragments per sample) using a modified protocol that enables more complete capture of footprints." The 3 growth conditions are: (1) "MOPS complete" MOPS minimal medium (Neidhart 1974) with 0.2% Glucose, supplemented with amino acids, vitamins, and micronutrients (2) "MOPS minimal" MOPS minimal medium with 0.2% Glucose (3) "MOPS complete - met" MOPS complete without methionine
Comments "The complete list of protein synthesis rates can be obtained at link (Table S1)." "Genes with few than 128 reads mapped (low confidence) in the sequencing data set are marked by square brackets."
Entered by Uri M
ID 110442