Proportion of types of endocrine cells in islets of Langerhans in pancreas

Range β cells 50%: α cells 35 - 40%: δ cells 10 - 15% %
Organism Human Homo sapiens
Reference Rorsman P, Braun M. Regulation of insulin secretion in human pancreatic islets. Annu Rev Physiol. 2013 75 :155-79. doi: 10.1146/annurev-physiol-030212-183754. p.156 3rd paragraphPubMed ID22974438
Primary Source Cabrera O, Berman DM, Kenyon NS, Ricordi C, Berggren PO, Caicedo A. 2006. The unique cytoarchitecture of human pancreatic islets has implications for islet cell function. Proc. Natl. Acad. Sci. USA 103: 2334–39PubMed ID16461897
Comments "A human pancreas contains ~1 million pancreatic islets (BNID 109966). The pancreatic islets consist of several types of endocrine cells, of which the insulin-secreting ß cells (50% of the cells in human islets), the glucagon-releasing a cells (35–40%), and the somatostatin-releasing d cells (10–15%) are the most important ones (primary source)." See BNID 109960, 103641
Entered by Uri M
ID 109967