Comparison of MBC (minimum bactericidal concentration), BC50 (median bactericidal concentration), and BC1 in various CKCs (concentration killing curves)

Range Table - link
Organism Bacteria Escherichia coli
Reference Liu YQ, Zhang YZ, Gao PJ. Novel concentration-killing curve method for estimation of bactericidal potency of antibiotics in an in vitro dynamic model. Antimicrob Agents Chemother. 2004 Oct48(10):3884-91. p.3888 table 1PubMed ID15388449
Comments "The parameter BC1 can be defined as BC50  [ln(N0  1)/r], which is the drug concentration at which only one colony survived and which is the least critical value of MBC in the CKC...As indicated in Table 1, MBC, BC50, r, and BC1 were derived from Fig. 2 to 6. BC50 and r are direct parameters of CKC, but they independently represent the median bactericidal concentration and the bactericidal intensity, respectively."
Entered by Uri M
ID 109911