| Range |
Extracellular glucose in the brain ~2.5: Plasma 7.6 mM
|
| Organism |
Rat Rattus norvegicus |
| Reference |
Routh VH. Glucose-sensing neurons: are they physiologically relevant? Physiol Behav. 2002 Jul76(3):403-13. p.404 right column 2nd paragraphPubMed ID12117577
|
| Primary Source |
Silver IA, Erecinska M. Glucose-induced intracellular ion changes in sugar-sensitive hypothalamic neurons. J Neurophysiol. 1998 Apr79(4):1733-45. AND Silver IA, Erecinska M. Extracellular glucose concentration in mammalian brain: continuous monitoring of changes during increased neuronal activity and upon limitation in oxygen supply in normo-, hypo-, and hyperglycemic animals. J Neurosci. 1994 Aug14(8):5068-76PubMed ID9535943, 8046468
|
| Method |
"Silver and Erecinska [primary sources] provided the only
data in which extracellular brain glucose levels were simultaneously
measured as plasma glucose levels were manipulated. In their studies, Silver and Erecinska clamped
peripheral glucose and measured extracellular brain glucose
using a glucose oxidase electrode." |
| Comments |
"Extracellular glucose in
the brain was about 2.5 mM in a fed, anesthetized rat whose
plasma glucose was 7.6 mM." |
| Entered by |
Uri M |
| ID |
108954 |