Speed of keratocytes (fibroblasts found in cornea) in G. mirabilis and C. salinus (maximal instantaneous rates)

Range 40 to 45 μm/min
Organism Fish
Reference Ream RA, Theriot JA, Somero GN. Influences of thermal acclimation and acute temperature change on the motility of epithelial wound-healing cells (keratocytes) of tropical, temperate and Antarctic fish. J Exp Biol. 2003 Dec206(Pt 24):4539-51. p.4547 right column top paragraphPubMed ID14610038
Method "Two types of analysis were used to quantitatively describe the directional component inherent in cell velocity. The first type of analysis plots the trajectory of each cell, beginning at the origin and oriented such that the first step taken by each cell is along the x-axis...The second type of analysis, plotting the cos (?) of vectors tangential to the cell trajectory versus path length traveled between each pair of vectors, revealed turning magnitudes in highly persistent cells that were not obvious in the trajectory analysis."
Comments "Keratocytes of the two eurythermal species, G. mirabilis and C. salinus, were capable of crawling the fastest, with maximal instantaneous rates of ˜40–45 µm·Min^–1. It is possible that there is some limit to keratocyte motility indicated by this maximal speed that might be reflected in an underlying cellular process governing motility rates." These are maximal instantaneous rates. Corresponds to 0.67 to 0.75µm/sec
Entered by Uri M
ID 106807