Conditions developed by T-cell receptor β and p53 double-knockout mice

Range 90% chronic inammation: 50-70% dysplasia: 70% adenocarcinoma %
Organism Mouse Mus musculus
Reference Ullman TA, Itzkowitz SH. Intestinal inflammation and cancer. Gastroenterology. 2011 May140(6):1807-16. p.1814 left column 4th paragraphPubMed ID21530747
Primary Source Kado S, Uchida K, Funabashi H et al., Intestinal microflora are necessary for development of spontaneous adenocarcinoma of the large intestine in T-cell receptor beta chain and p53 double-knockout mice. Cancer Res. 2001 Mar 15 61(6):2395-8.PubMed ID11289103
Method (primary source abstract:) histopathological examination
Entered by Uri M
ID 106628