Number of proteins per mRNA transcript in genes that were identified at both the mRNA and protein level

Value 2800 Proteins/transcript
Organism Mammalian tissue culture cell
Reference Schwanhäusser B, Busse D, Li N, Dittmar G, Schuchhardt J, Wolf J, Chen W, Selbach M. Global quantification of mammalian gene expression control. Nature. 2011 May 19 473(7347):337-42. p.338 right column 2nd paragraph and fig.2b Corrected value is from Schwanhäusser B et al., Corrigendum: Global quantification of mammalian gene expression control. Nature. 2013 Mar 7 495(7439):126-7. doi: 10.1038/nature11848. p.126 right column 2nd paragraphPubMed ID21593866, 23407496
Method Stable isotope labelling by amino acids in cell culture (SILAC)
Comments NIH3T3 (mouse fibroblast) cells. mRNA median=17, Protein median=16,000. Divide protein median by transcript median to arrive at value.
Entered by Uri M
ID 106376