Length of centromeric DNA in human chromosomes

Range 0.2-7 megabases
Organism Human Homo sapiens
Reference Vagnarelli P, Ribeiro SA, Earnshaw WC. Centromeres: old tales and new tools. FEBS Lett. 2008 Jun 18 582(14):1950-9. p.1950 right column bottom paragraphPubMed ID18435926
Primary Source [16] J.J. Maio , DNA strand reassociation and polyribonucleotide binding in the African green monkey, Cercopithecus aethiops . J. Mol. Biol., 56, (1971), 579– 595. [17] K.H. Choo , B. Vissel , A. Nagy , E. Earle , P. Kalitsis , A survey of the genomic distribution of alpha satellite DNA on all human chromosomes, and derivation of a new consensus sequence. Nucleic Acids Res., 19, (1991), 1179– 1182.PubMed ID4995480, 2030938
Comments P.1950 right column bottom paragraph: "In general, human centromeric DNA consists of arrays comprising 0.2–7 megabases of a 171 bp α-satellite motif repeated in tandem head-to-tail arrangement [primary sources]. This α-satellite DNA is present at all natural human centromeres [ref 18]. α-Satellite can be subdivided in two types [refs 19,20]."
Entered by Paul Jorgensen
ID 105402