Translation time of apolipoprotein B

Value 14 min
Organism Human Homo sapiens
Reference Olofsson SO, Boström K, Carlsson P, Borén J, Wettesten M, Bjursell G, Wiklund O, Bondjers G., Structure and biosynthesis of apolipoprotein B. Am Heart J. 1987 Feb113(2 Pt 2):446-52.PubMed ID3812204
Primary Source K Bostrom et al, Pulse-chase studies of the synthesis and intracellular transport of apolipoprotein B-100 in Hep G2 cells,J. Biol. Chem. 1986 261: 13800-13806PubMed ID3020051
Method Pulse-chase methodology in the Hep-G2 cell (a human liver carcinoma cell line)
Comments Apolipoprotein B gene sequence spans 13,689 nucleotides from the initiation to the stop codon. Thus the messenger has the capacity to code for 4563 amino acids, corresponding to a translation rate of 5 aa/sec
Entered by Uri M
ID 104599