Reduction in amount of beta adrenoreceptor following 72 hours agonist infusion
Value | 45 % |
---|---|
Organism | Rat Rattus norvegicus |
Reference | Lu XY, Barnett DB. Differential rates of down regulation and recovery of rat myocardial beta-adrenoceptor subtypes in vivo. Eur J Pharmacol. 1990 Jul 17182(3):481-6.PubMed ID2171948 |
Method | isoprenaline infusion, sacrifice, homogenization of tissue and centrifugation |
Comments | Decrease from 19.8 to 11.1 femtomol/mg. See table 1 |
Entered by | Uri M |
ID | 103622 |