catalytic rate of rhodopsin in vivo

Range 600-1300 sec^-1
Organism Cow Bos Taurus
Reference Heck M, Hofmann KP. Maximal rate and nucleotide dependence of rhodopsin-catalyzed transducin activation: initial rate analysis based on a double displacement mechanism. J Biol Chem. 2001 Mar 30276(13):10000-9.PubMed ID11116153
Method In this study on photoactivated rhodopsin (R*) and the rod G protein, G(t), researchers have used kinetic light scattering, backed by direct biochemical assays, to follow G protein activation.
Comments Maximal catalytic rates per photoexcited rhodopsin are 600 G(t)/s at 22 degrees C and 1300 G(t)/s at 34 degrees C.
Entered by Uri M
ID 103611