Ratio between mitochondrial DNA and nuclear DNA

Value <= unitless Range: <0.01 unitless
Organism Eukaryotes
Reference Robin ED, Wong R. Mitochondrial DNA molecules and virtual number of mitochondria per cell in mammalian cells. J Cell Physiol. 1988 Sep136(3):507-13. p.507 left column 2nd paragraphPubMed ID3170646
Primary Source Lewin, B. (198Oa) Gene Expression 2. Eucaryotic Chromosomes, 2nd Ed. New York: John Wiley and Sons, Inc., p. 590.
Comments P.507 left column 2nd paragraph: "The methods of measurement involved electron-microscopic examination of DNA in ultra-thin sections of mitochondria or isolation of mitochondrial DNA by differences in buoyant density or chemical analyses of limited specificity (Bogenhagen and Clayton, 1974). As mt DNA only represents less than 1% of total cell DNA (primary source), contamination with extramitochondrial DNA makes the results dubious."
Entered by Uri M
ID 102917