Absolute abundance of p53 in cell

Range ~160,000 (21,000 to 195,700) Copies/cell
Organism Human Homo sapiens
Reference Ma L, Wagner J, Rice JJ, Hu W, Levine AJ, Stolovitzky GA. A plausible model for the digital response of p53 to DNA damage. Proc Natl Acad Sci U S A. 2005 Oct 4 102(40):14266-71. Supplementary text - link p.9 2nd paragraph PubMed ID16186499
Method Supplementary text p.10 2nd paragraph: "The basal concentration of p53 was measured using human p53 Elisa kit (Biosource, Camarillo, CA) according to the manufacturer’s instruction." Griffin et al., Human Anti-antibody Response, p.508 2nd paragraph:"ELISA [Enzyme-linked immunosorbant assay]...is a sensitive immunoassay that uses an enzyme linked to an antibody or antigen as a marker for the detection of a specific protein, especially an antigen or antibody."
Comments
Entered by Alex Loewer
ID 100420