Average width of planar Purkinje cell dendritic tree
Please note: The entry will be shown to all once approved by the database administrator.
Value | 7 µm |
---|---|
Organism | Mouse Mus musculus |
Reference | Li L et al., Visualizing the distribution of synapses from individual neurons in the mouse brain. PLoS One. 2010 Jul 9 5(7):e11503. doi: 10.1371/journal.pone.0011503. p.7 right column top paragraphPubMed ID20634890 |
Primary Source | Mukamel EA, Nimmerjahn A, Schnitzer MJ (2009) Automated analysis of cellular signals from large-scale calcium imaging data. Neuron 63: 747–760.PubMed ID19778505 |
Method | Primary source abstract:"[Investigators] used automated procedures to analyze data recorded by two-photon Ca(2+) imaging in the cerebellar vermis of awake behaving mice." |
Comments | p.6 left column bottom paragraph to right column top paragraph:"[Investigators’] finding [BNID 112026] implies that granule cells make denser connections in the molecular layer than previously thought. A recent study using calcium imaging suggests that the width of planar Purkinje cell dendritic tree is on average 7µm [primary source]. Given that each parallel fiber usually forms 1–2 synapses with a Purkinje cell [PMID 16759785], it is possible that a parallel fiber synapses with almost all Purkinje cells whose dendritic branches are within its reach." keywords:cns,central nervous system,brain,neuron,synapse |
Entered by | Uri M |
ID | 112027 |