Range |
3.8e-10 at URA3: 6.44e-10 at CAN1 1/bp/generation
|
Organism |
Budding yeast Saccharomyces cerevisiae |
Reference |
Lang GI, Murray AW. Estimating the per-base-pair mutation rate in the yeast Saccharomyces cerevisiae. Genetics. 2008 Jan178(1):67-82. doi: 10.1534/genetics.107.071506. p.68 right column top paragraphPubMed ID18202359
|
Method |
"Typically, fluctuation assays are performed in test
tubes: however, to increase the throughput, [researchers] perform
the assays in 96-well plates." |
Comments |
"Combining...estimates
of phenotypic mutation rates and locus-specific
effective target sizes, [researchers] conclude that the per-base-pair
mutation rates at URA3 and CAN1 are 3.80?10^-10 and
6.44?10^-10/bp/generation, respectively, suggesting that
the mutation rate varies across the yeast genome." |
Entered by |
Uri M |
ID |
110018 |