Mutation rates at URA3 and CAN1
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| Range | 3.8e-10 at URA3: 6.44e-10 at CAN1 1/bp/generation |
|---|---|
| Organism | Budding yeast Saccharomyces cerevisiae |
| Reference | Lang GI, Murray AW. Estimating the per-base-pair mutation rate in the yeast Saccharomyces cerevisiae. Genetics. 2008 Jan178(1):67-82. doi: 10.1534/genetics.107.071506. p.68 right column top paragraphPubMed ID18202359 |
| Method | "Typically, fluctuation assays are performed in test tubes however, to increase the throughput, [researchers] perform the assays in 96-well plates." |
| Comments | "Combining...estimates of phenotypic mutation rates and locus-specific effective target sizes, [researchers] conclude that the per-base-pair mutation rates at URA3 and CAN1 are 3.80?10^-10 and 6.44?10^-10/bp/generation, respectively, suggesting that the mutation rate varies across the yeast genome." |
| Entered by | Uri M |
| ID | 110018 |