Lifespan of long-term self-renewing hematopoietic stem cells (LT-HSC)
Please note: The entry will be shown to all once approved by the database administrator.
| Value | 57 Days |
|---|---|
| Organism | Mouse Mus musculus |
| Reference | Cheshier SH, Morrison SJ, Liao X, Weissman IL. In vivo proliferation and cell cycle kinetics of long-term self-renewing hematopoietic stem cells. Proc Natl Acad Sci U S A. 1999 Mar 16 96(6):3120-5. p.3123 left column 2nd paragraph and p.3125 left column top paragraphPubMed ID10077647 |
| Method | Study of BrdUrd incorporation (Bromodeoxyuridine) kinetics |
| Comments | "[Researchers'] data demonstrate that LTHSC enter the cell cycle in an asynchronous manner, that proliferation was not dominated by a few clones, and that on average 99% of LT-HSC divide every 57 days." |
| Entered by | Uri M |
| ID | 109232 |