Spliceosome composition

Range 5 snRNAs: ~100 core proteins molecules/cell
Organism Eukaryotes
Reference Hoskins AA et al., Ordered and dynamic assembly of single spliceosomes. Science. 2011 Mar 11 331(6022):1289-95. doi: 10.1126/science.1198830. p.1289 left columnPubMed ID21393538
Primary Source Fabrizio P, Dannenberg J, Dube P, Kastner B, Stark H, Urlaub H, Lührmann R. The evolutionarily conserved core design of the catalytic activation step of the yeast spliceosome. Mol Cell. 2009 Nov 25 36(4):593-608. doi: 10.1016/j.molcel.2009.09.040.PubMed ID19941820
Comments "The spliceosome is composed of five small nuclear RNAs (snRNAs) and ~100 core proteins minimally required for activity invitro (primary source)."
Entered by Uri M
ID 109052