Genome-wide recombination rate
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Value | 22.8 events/cell Range: ±0.4 events/cell |
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Organism | Human Homo sapiens |
Reference | Jianbin Wang, H. Christina Fan, Barry Behr and Stephen R. Quake Genome-wide Single-Cell Analysis of Recombination Activity and De Novo Mutation Rates in Human Sperm, Cell 150, 402–412, July 20, 2012 p.403 right column bottom paragraphPubMed ID22817899 |
Method | p.403 left column 2nd paragraph: "[Researchers] collected a sperm sample from a 40-year-old Caucasian individual (P0) whose genome has been sequenced (Pushkarev et al., 2009), clinically annotated (Ashley et al., 2010), and haplotype phased (Fan et al., 2011)." |
Comments | "At a genome-wide scale, the recombination rate of 22.8±0.4 SE (±3.7 SD) events per cell agrees well with the average male results implied from other methods, such as cytological imaging (49.8±0.4 SE [±4.3 SD] MLH1 loci within the tetraploid spermatocytes [Sun et al., 2004] and data inference (24.0±0.2 SE [±2.7 SD] from Caucasian pedigrees [Cheung et al., 2007])." |
Entered by | Uri M |
ID | 108035 |