Fraction of tumors that have whole-chromosome aneuploidy or a karyotype that is not a multiple of the haploid complement

Range >90 %
Organism Human Homo sapiens
Reference Sheltzer et al., Aneuploidy drives genomic instability in yeast. Science. 2011 Aug 19 333(6045):1026-30. p.1026 left columnPubMed ID21852501
Primary Source Torres EM, Williams BR, Amon A. Aneuploidy: cells losing their balance. Genetics. 2008 Jun179(2):737-46. AND Weaver BA, Cleveland DW. Does aneuploidy cause cancer? Curr Opin Cell Biol. 2006 Dec18(6):658-67.PubMed ID18558649, 17046232
Comments Whole-chromosome aneuploidy—or a karyotype that is not a multiple of the haploid complement—is found in greater than 90% of human tumors and may contribute to cancer development (primary sources).
Entered by Uri M
ID 107330