Mutation rate per base pair per replication

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Value 7.2E-11 mutation/bp/replication Range: Table - link mutation/bp/replication
Organism Bread mold Neurospora crassa
Reference Drake JW, Charlesworth B, Charlesworth D, Crow JF. Rates of spontaneous mutation. Genetics. 1998 Apr148(4):1667-86. p.1670 table 4PubMed ID9560386
Primary Source Drake JW, A constant rate of spontaneous mutation in DNA-based microbes.Proc Natl Acad Sci U S A. 1991 Aug 15 88(16):7160-4 Table 1 Table - link PubMed ID1831267
Method study of spontaneous mutations (resting genomes mutate in a time-dependent, replication independent fashion because they accumulate spontaneous DNA damage that engenders mutations when DNA replication resumes, and that may even alter transcription to produce a mutant phenotype before replication).
Entered by Uri M
ID 106747