Cell density of a defined medium that contains the maximum non-inhibitive concentration of nutrients

Value 15 g (dry weight)/liter
Organism Bacteria Escherichia coli
Reference Shiloach J, Fass R. Growing E. coli to high cell density-a historical perspective on method development. Biotechnol Adv. 2005 Jul23(5):345-57.PubMed ID15899573
Primary Source Lee SY. High cell-density culture of Escherichia coli. Trends Biotechnol. 1996 Mar14(3):98-105.PubMed ID8867291
Comments Note-Counter-intuitively, the cell density (and the OD) that can be reached when maximal not-inhibitive concentration of nutrient is supplied is lower than cell density when lower concentrations of nutrient are given. To get higher cell densities (54-190 g/L, BNID 104942, 104943) lower concentrations of nutrient are actually needed.
Entered by Uri M
ID 105323