| Value |
0.12
pN
|
| Organism |
Bacteriophage Lambda |
| Reference |
Garcia HG, Grayson P, Han L, Inamdar M, Kondev J, Nelson PC, Phillips R, Widom J, Wiggins PA. Biological consequences of tightly bent DNA: the other life of a macromolecular celebrity. Biopolymers. 2007 Feb 585(2):115-30.PubMed ID17103419
|
| Method |
Model of tightly packed viral DNA. Equation (3) on page 118 Force bend=(k*epsilonP)/(2*R^2) where k=flexural rigidity,epsilonP=persistence length,R=radius of bent DNA. Taking R of lambda phage, 29nm |
| Comments |
pN=picoNewton=10^-12Newton. This is the force required for initial stage of packaging. It increases as more DNA is wound around 'inversed spool'. This is a relatively small force compared to the maximum forces exerted by molecular motors, which are typically in the pN regime. |
| Entered by |
Uri M |
| ID |
103124 |