Mutation rate per base pair per replication
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| Value | 2.2E-10 mutation/bp/replication Range: Table - link mutation/bp/replication |
|---|---|
| Organism | Budding yeast Saccharomyces cerevisiae |
| Reference | Drake JW, Charlesworth B, Charlesworth D, Crow JF. Rates of spontaneous mutation. Genetics. 1998 Apr148(4):1667-86. p.1670 table 4PubMed ID9560386 |
| Method | The typical procedure is to estimate C (the reciprocal of the efficiency of mutation detection), then to calculate the mutant frequency f, then the mutation rate µt of the measured target sequence, then the mutation rate µbp of the average base pair (dividing µt by the size of the target sequence), then the mutation rate µg of the entire genome (multiplying µbp by the number of base pairs per genome). |
| Entered by | Ron Milo - Admin |
| ID | 100457 |