Mutation rate per base pair per replication
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Value | 2.3E-10 mutation/bp/replication Range: Table - link mutation/bp/replication |
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Organism | Nematode Caenorhabditis elegans |
Reference | Drake JW, Charlesworth B, Charlesworth D, Crow JF. Rates of spontaneous mutation. Genetics. 1998 Apr148(4):1667-86. p.1673 Table 5PubMed ID9560386 |
Method | Combining mutation rates that have been determined for five loci: Taking the gene sizes as three times the number of codons plus 100 b for regulatory and splicing sequences, using an average C (The variously calculated ratio of total mutations to observed mutations)=3.12, dividing by average number of divisions prior to gamete maturation= 9.1 |
Comments | Range of 1.1?10^-10 to 4.8?10^-9mutations per site per generation according to PMID 17637734 p.622 right column 3rd paragraph. Genome size of 8X10^7bp given in table. |
Entered by | Ron Milo - Admin |
ID | 100287 |