Euchromatic genome Size

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Value 1.2e+8 Base pairs
Organism Fruit fly Drosophila melanogaster
Reference Adams MD et al, The genome sequence of Drosophila melanogaster. Science. 2000 Mar 24 287(5461):2185-95.PubMed ID10731132
Method Genome assembly relied on the use of several types of data, including clone-based sequence, whole-genome sequence from libraries with three insert sizes (2 kb, 10 kb, and 130 kb), and a Bacterial Artificial Chromosome (BAC)-based sequence-tagged site (STS) content map. The combination of these resources resulted in a set of ordered contigs spanning nearly all of the euchromatic region on each chromosome arm (p. 2194).
Comments The Drosophila genome is ~180 Mb in size, a third of which is centric heterochromatin. The 120 Mb of euchromatin is on two large autosomes and the X chromosome. The small fourth chromosome contains only ~1 Mb of euchromatin. The heterochromatin consists mainly of short, simple sequence elements repeated for many megabases, occasionally interrupted by inserted transposable elements, and tandem arrays of ribosomal RNA genes (p. 2185).
Entered by Ron Milo - Admin
ID 100199